Prosopography Assignment Example | Topics and Well Written Essays - 500 words

Prosopography - Assignment Example They likewise have a conventional authority structure, where there is a committee of strict pioneers, explicitly men, who settles on choices in the interest of the whole network. Moreover, this network will in general develop apple trees, cherry along with noteworthy measures of wheat. Dominant part of the Druze family will in general develop their own natural products, vegetables and prepare their own bread. Druze ladies customarily dress in long blue or white dresses with a white headscarf, while their men had surrendered their customary methods of dressing, explicitly the shirwal and develop mustache (Gordon, 12). Their homes are hardly outfitted, with a trademark low wooden table and slender pads lined against the dividers. Their language has an Egyptian source; their language can without much of a stretch be perceived because of the way that they have a sharp way to express the letter â€Å"q†. Fundamentally, the life of Druze man spins around his family and participation of strict gatherings on each Thursday night. They have a high feeling of cordiality in their way of life and will in general visit each other in their homes (Gordon, 14). With respect to separate, it is an uncommon activity among the Druze; in any case, men may start separate from when a spouse neglects to hold up under kids. Therefore, the Syrian Druze has an exceptional religion, which can be followed back to Egypt; as a rule, their Druze religion has been repudiated by Muslims (Gordon, 16). The Community had a positive relationship with the Assad system, essentially attributable to the way that Assad figured out how to look for colossal help from the minority networks; be that as it may, right now the network is torn in the middle of supporting Assad and the Islamist radicals. A portion of the Druzes has guaranteed that Assad bombed them by not giving them weapons to shield themselves from the Jabhat Al-Nusra assaults (Gordon, 22). The Druze of Syria are less fortunate when cont rasted with other minority networks; this has been ascribed to the way that they have spent numerous years on war issues instead of

The First Thanksgiving Essays - Plymouth, Massachusetts,

The First Thanksgiving THE FIRST THANKSGIVING On September 6, 1620, 102 men, ladies and kids from England boarded a little load vessel called the Mayflower and set sail for the New World. The travelers left their homes in England looking for strict opportunity from the King of England. Today they are known as pioneers. In the wake of conquering two months adrift, crossing the blustery Atlantic Ocean, the Pilgrims at long last arrived off the shore of the New World. In the freezing December waters, they moored the Mayflower and sent an arrival gathering to what is presently Plymouth Harbor sea shore. To make sure about the little arrival vessel against the downpour and winds, they attached it to a huge stone - Plymouth Rock - thus starts the legend of the first Thanksgiving story. The Pilgrims wound up in an unforgiving new condition. In winter, they gradually constructed a settlement at the site of a surrendered Pawtuxet Indian town. Not used to chasing or angling, they battled to discover food. Many were starving. The future looked hopeless. Huge numbers of the pioneers didn't endure the primary winter. When spring showed up, they despite everything had not met the Indians. Rather, they lived in dread of their concealed neighbors dependent on savage stories they got notification from scouts. At the point when April showed up, the team of the Mayflower raised its sails and set off for England, offering to take any Pilgrim who wished to come back to England. Confronted with the decision of the unforgiving New World, or the strict prejudice of the King, they all remained. At some point, a solitary Indian man strolled into the settlement. He lifted his hand in companionship to the pioneers. The Pilgrims invited this outsider named Samoset. Samoset acquainted the Pilgrims with his boss, Massasoit, and his mediator, Squanto. Squanto communicated in English since he had been caught as a kid by brokers who had gone to the New World looking for slaves. Squanto was taken to England and lived there numerous prior years coming back to the New World. Only he comprehended that the Pilgrims didn't have the foggiest idea how to chase or fish - that they would pass on without assistance in the New World. Squanto and Chief Massasoit stretched out their kinship to the Pilgrims. They told them the best way to get fish with nets and how to develop corn, pumpkins, potatoes and squash - nourishments from the New World. The Indians demonstrated the Pilgrims where to chase turkey and deer, and where to assemble nuts and berries. They disclosed to the Pilgrims that the land was ace of the individuals who strolled and lived there. The gather of 1621 saw the satisfaction of their works. The Pilgrims had developed grain, corn, pumpkins, and beans. The pioneers toiled to assemble their abundance; and in a debt of gratitude is in order for their fortune, chose to respect the land with an exceptional day of thanks and festivity. In fellowship and appreciation to Squanto, Chief Massasoit and the Indian individuals, they welcomed their new companions to participate in the blowout. The Pilgrims went through days getting ready for the blowout. The men chased ducks and turkeys, while the ladies prepared food and adorned the table. At the point when the day at long last showed up, the Pilgrims were astonished to see not 10, not 20, yet 90 Indians moving toward the town! They carried with them an abundance all their own. For three days, the Indians and Pilgrims ate and offered gratitude to the land for the reap. It was a festival of companionship and much appreciated; however the vast majority of all, it was a festival of opportunity. Neither the Indians nor the Pilgrims recognized what they had started, however from this festival rose Thanksgiving as we probably am aware it today. We have been praising it as an exceptionally American occasion from that point forward. In 1863, President Lincoln authoritatively announced the last Thursday in November an occasion of thanksgiving and acclaim, thus it remains today. Cheerful Thanksgiving! History Essays

4 Writing Secrets to Improve Your Social Media Accounts

4 Writing Secrets to Improve Your Social Media Accounts Make Money Online Queries? Struggling To Get Traffic To Your Blog? Sign Up On (HBB) Forum Now!4 Writing Secrets to Improve Your Social Media AccountsUpdated On 10/10/2019Author : Ram kumarTopic : Social MediaShort URL : https://hbb.me/35p7KCw CONNECT WITH HBB ON SOCIAL MEDIA Follow @HellBoundBlogSocial media is a great way to connect with family and friends using multimedia and written word. However, the trend of using social media for business purposes has reached its peak and is continuing to grow.With company leaders seeking to be the first choice, the competition has become real. To succeed, you need to improve your social media accounts to stand out. One of the best ways to do that is to focus on the way you write social media posts.Here are four writing secrets that can be used to improve social media accounts and make them look more credible.Don’t cut words or use social media abbreviationsWhen writing on social media, the temptation of shortening whenever you get the chan ce, is real. Some of the most popular ways to do this are to use unofficial abbreviations like BTW, FR, RN, which means By The Way, For Real and Right Now.Other people may opt to use numbers that sound like a particular word or part thereof. Those numbers are used like this b4, going 2 the office, etc. Using those abbreviations can hinder the social media content visibility of that post because when people search for it in plain English, they won’t find it.These tips can help build a great career in social marketing. As you pursue it by studying, use thebest essay editing service in the UKto edit your essays. The online expert writers can also help you with term papers, thesis and dissertation writing and researching.Writing professionally doesn’t mean that it has to be uptight and so serious that it loses its appeal. On the contrary, you can add humor and puns here and there to attract new business. Before you go on interjecting humor on social media posts, try to define your reader and then rule out what would be appropriate.Understand homophonesHomophones can be a real pain when typing in a hurry because you can end up spelling “to” as “too” and making other similar mistakes.It is hard to detect homophone errors while you are writing. But a fundamental understanding of what homophones should be avoided can be very useful. Understanding homophones will help you as you learn how to write better for social purposes and normal occasions.Don’t rely solely on spell check to do the work for you because sometimes they can be missed by the software you use. Besides, homophone mistakes can grow to you and they will end up affecting your life outside social media, or where you can use a spell checker.READ6 Reasons Why Being Popular In Social Media MattersTo avoid this, proofread all social media posts before you make the social media post seen by all those following you.Focus on the grammarSocial media is well-known for its grammar checking police that correct other users at every mistake they make. Grammar indeed is one of the most important elements of writing.That is why you shouldn’t fall victim to grammatical errors because your followers will start discrediting and ridiculing the posts you make. You need to ensure that the best grammar is used all the time before the post goes online.Instead of posting a hurried post that has a high potential of grammatical errors, take your time and work through it to minimize errors. Punctuation marks and being consistent with the tense of each sentence are some points to follow-up on.This problem can be worked by using tools such as Grammarly and Hemingway App that give you suggestions on where the post can be improved.Read the draft post aloudThe best way to resolve most errors, when you write, is to proofread the post a few times before posting it. As you read through, it will be easy to identify problems because wherever you get stuck when reading it is where you should edit.The proc ess will save you the struggle of trying to edit or delete the post once it has been posted. When you’re reading the post for the final time, read it out aloud. Reading it out loud will help you listen to the context and you will hear if it makes perfect sense and is free of grammatical errors.The bottom lineSocial media posts have evolved, they aren’t only social now, but they are marketing vehicles for different companies. Social marketers and other users of these platforms must recognize the importance of using simple English that is free of errors. Nip it while it is still at the buds by using proper language even on social media and this will result in improved writing skills.Author Bio:Emma Rundle is a digital marketing expert working as a consultant for online writing services. Her main focus is to help the services reach the students who need writing services and convey the right message effectively. She also focuses on the shareability and likability part of the message . In her free time, she practices mindfulness, reads mystery novels and plays tennis.

The Cape Cod House Style in Pictures and Text

The Free Trade Area of the Americas Summit Free Essay Example, 1750 words

According to the plan, the city on Miami PD was to lead the joint law enforcement agencies. However, the MDPD did not relinquish command to the Miami PD or any other force in the mission instead the MDPD made respondents to the Miami PD requests (12). Despite the joint operation, disunity of the FTAA control made it difficult and impracticable to determine police actions accountability and lead to throwing blames against each other. This resulted in answers like we don t know who is responsible for that as a response to questions about specific police actions (9). The third issue is about the use of force in operations by the joint law enforcement team. According to MDPD during the public hearing, only two types of weapons were employed. The less-lethal weapons particularly the pepper spray canister and the pepper ball ammunition were used. The use of the two did not conform to the operating standard procedure which in chapter 31 states, Chemical agents will not be used unless a ll reasonable efforts of control have failed. (13). As about prisoner processing procedure, there was no significant problem since prisoner processing sites existed at Metrorail station. We will write a custom essay sample on The Free Trade Area of the Americas Summit or any topic specifically for you Only $17.96 $11.86/pageorder now However, those who were arrested complained of too-tight handcuffs but no one filed plaintiff during the retention. Finally was the issue of community labor. Prior to the event, the city on Miami PD met AFL-CIO representatives to plan the cause of action as about bus routes. The plans were a casual and verbal agreement with Miami police and did not inform the MDPD officers. The MDPD blocked some routes that contradicted the agreement something that led to AFL-CIO and FLARA protests. They felt that the police did not accord protesters same protection as it did with the FTAA ministerial. Events to show police readiness to defend the ministerial from the attack were more evident than measures to protect committed peaceful protesters (14).

Monopoly Monopolistic Market Situation - 1126 Words

The concept of monopoly relates to a situation where a large part of the market if not all, is controlled by one company or group of companies. Monopoly identifies with the market share ownership where one organization supplies a given product to the market in the absence of alternative or substitute suppliers (Trageks, 2010). The case scenario in this study presents a monopolistic market situation. The fact that Futures Unlimited Corporation is the single license owner approved to distribute and control plutonium presents a monopolistic situation. Monopolistic markets post different results on organizations depending on the company s management decisions. Although many monopolies employ the single price strategy in ensuring the maximization of profits, the effectiveness of this model posits a question of fact. A single priced monopoly indicates that elasticity in demand affects a single price monopoly in such a way that increased prices lead to decreased consumption of the commod ities. In this scenario, the monopolistic situation leads to the reduction of revenue as well as profits. A monopolistic organization will only make profits in the situation where marginal revenues exceed marginal costs. In the event a monopolistic market increases production where revenue equals costs, the company experiences decreased revenues as well as profitability. A single priced monopoly likely has a reducing effect on the company s profitability with an extra output. However, theShow MoreRelatedEco 204 Final Paper1488 Words   |  6 Pagesof a situation in a free market to combine an already successful business. They have no competition and they are ready to sell! The management consulting firm they hired will take charge of the advertising, the lay-off of employees, and the new way of operating. 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Gatsbys Corruptive Nature Essay Example For Students

Gatsbys Corruptive Nature Essay The Great Gatsby , written by F. Scott Fitzgerald is a portrayal of the withering of the American Dream. The American Dream promises prosperity and self-fulfillment as rewards for hard work and self-reliance. A product of the frontier and the west, the American Dream challenges people to have dreams and strive to make them real. Historically, the Dream represents the image of believing in the goodness of nature. However, the American Dream can be interpreted in different ways. While some may strive for spiritual goodness and excellence, others take the dream to represent purely materialistic values. This is the case of Jay Gatsby, and Fitzgerald shows through conflict and symbolism that such a materialistic interpretation of the American Dream is the very cause of Gatsbys downfall. Gatsbys personal dream symbolizes the larger American dream where all have the opportunity to get what they want.(Prasad This blured version of the American Dream is represented primarily by the conflict between the newly rich and the established rich, the East Eggers and the West Eggers. West Egg is the home of Jay Gatsby and those like him who have made huge fortunes but who lack the traditions that come with inherited wealth. The West Eggers live in a crude world, coming from the adoption of wealth as their only standard in achieving the American Dream. The East Eggers, represented in The Great Gatsby by the Buchanans, have the inherited traditions that come with wealth and lack the crudeness of the West Eggers. They have been corrupted by the purposelessness and ease that their money has provided. Due to their inherited traditions, the East Eggers naturally regard any change in the social hierarchy as a threat to the entire structure of society. An example of this is shown when Tom Buchanan makes a remark about the seperation of the family and eventual intermarriage between black and white.The idea is if we dont look out the white race will be utterly submerged. Its all scientific stuff; its been proved. Its up to us, who are the dominant race, to watch out or these other races will have control of things.(17) Thus, the wealth of the West Eggers and that of the East Eggers result in similar human differences, though shown differently. That is why West Egg and East Egg, apppear so dissimilar, are identical. They are both withering away from the promise of the American Another example of the corrupt American Dream is the automobile, a classic symbol of material wealth in America. In The Great Gatsby, Jay Gatsby is obsessed with a life of materialism. He owns a remarkable automobile whose appearance is envied by many. It was a rich cream color, bright with nickel, swollen here and there in its monstrous length with triumphant hat-boxes and super-boxes and tool-boxes, and terraced with a labyrinth of wind-shields that mirrored a dozen suns.(68) Gatsbys car is an overblown item created by wealth to fulfill the American Dream of personal material success. It is, however, Gatsbys car that kills Myrtle Wilson when Daisy runs her over. This indirectly leads to Gatsbys own death and portrays Fitzgeralds theme that basing the Dream on materialism alone is ultimately destructive. Along with the automobile, Jay Gatsby himself is a symbol of the corruption of the American Dream. He is a romantic dreamer who seeks to fulfill his life by earning his wealth as a mobster. Gatsby does not change much in the course of the novel because his whole life is devoted to the fulfillment of a romantic dream created that is inconsistent with the realities of society. At a very early age Gatsby vowed to love and to marry Daisy Buchanan. His lack of wealth led Daisy into the arms of another more prosperous man, Tom Buchanan. Gatsby believed that he could win Daisy back with money, and that he could get the life she wanted if he paid for it. .uf271c14ffbd195c210fdf965d0faa29c , .uf271c14ffbd195c210fdf965d0faa29c .postImageUrl , .uf271c14ffbd195c210fdf965d0faa29c .centered-text-area { min-height: 80px; position: relative; } .uf271c14ffbd195c210fdf965d0faa29c , .uf271c14ffbd195c210fdf965d0faa29c:hover , .uf271c14ffbd195c210fdf965d0faa29c:visited , .uf271c14ffbd195c210fdf965d0faa29c:active { border:0!important; } .uf271c14ffbd195c210fdf965d0faa29c .clearfix:after { content: ""; display: table; clear: both; } .uf271c14ffbd195c210fdf965d0faa29c { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .uf271c14ffbd195c210fdf965d0faa29c:active , .uf271c14ffbd195c210fdf965d0faa29c:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .uf271c14ffbd195c210fdf965d0faa29c .centered-text-area { width: 100%; position: relative ; } .uf271c14ffbd195c210fdf965d0faa29c .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .uf271c14ffbd195c210fdf965d0faa29c .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .uf271c14ffbd195c210fdf965d0faa29c .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .uf271c14ffbd195c210fdf965d0faa29c:hover .ctaButton { background-color: #34495E!important; } .uf271c14ffbd195c210fdf965d0faa29c .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .uf271c14ffbd195c210fdf965d0faa29c .uf271c14ffbd195c210fdf965d0faa29c-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .uf271c14ffbd195c210fdf965d0faa29c:after { content: ""; display: block; clear: both; } READ: Hard Rock Operations Management and Productivity of the Staff Essay He wanted to do away with time in order to obliterate the four years Tom and Daisy had together. Gatsby wanted to repeat the past, Im going to fix everything just the way it was before. Shell see . . ..(117) Gatsbys romantic disregard for

The Facts Of Aids Essays - HIVAIDS, Health, Medicine, HIV, Virus

The Facts Of Aids AIDS is the plague of the 20th century, but how much do we really know about this deadly disease? HIV is a virus that gets into the body and flows through the bloodstream. AIDS is the disease that is caused by HIV. Once you are diagnosed as HIV positive, you do not automatically have AIDS. There is a possibility of being HIV positive, and not having AIDS. Most people do not know it is the infections that break down the body's immune system rather than the AIDS that kills paients. HIV can be prevented in many ways, but they are not always followed. People die when they don't play it safe. That's why we have to spread the word on prevention. There a three main ways the HIV can be spread: 1. sexual intercourse 2. intravenous drugs 3. blood transfusions (which are very rare now because all blood is tested) HIV is spreading like wild fire among adolescents because they don't believe it can happen to them. Sixty-one percent of 14-21 year olds are engaged in sexual intercourse. The problem we have to deal with is the spreading of this disease among our generation. A small percentage of people who use condoms still get HIV because: 1. misuse of condom 2. use of drugs or alcohol which can impair judgment or proper use 3. the condom could be defected The AIDS virus can be spread in many ways. AIDS can be transmitted by direct contact of bodily fluids from an infected male or female. The AIDS infected blood contaminates uninfected blood. The three most common ways of transmission are: sexual intercourse, blood transfusions of infected blood, and the sharing of intravenous needles which may have contaminated blood still in them. The virus cannot be contracted in many of the ways people think it can. There is a very low concentration of the virus in tears and saliva, so these cases of transmission are very rare. There are no known cases of transmission through mosquitoes or any other animals. Another common way of AIDS transmission is mother to child transmission. The virus can be transmitted to the child from the mother before or during the delivery of the baby. The other mother to child transmission case is through the breast milk that he/she is fed in the early stages of the child's life. In the first stages of HIV, the symptoms don't show up. People can live with AIDS for years without knowing it. Blood tests at the doctor will show antibodies after they form to fight the AIDS virus, but it takes the antibodies three months to show up. That means that if you take a blood test right after you have sex, the virus won't show up for another three months. In the second stage, the virus grows within the white blood cells and destroys them. When most of the cells are destroyed, the immune system is destroyed and the body weakens. Some symptoms they might form are: they begin feeling tired, loose weight. They may develop a cough, diarrhea, fever, or sweating at night. With HIV a cold is more threatening to them than to a person without the disease. In stage three, the AIDS virus has nearly destroyed the body's immune system. The body has great difficulty fighting off germs. Also, patients can develop a rare type of cancer called Kaposi's sarcoma. AIDS doesn't kill anyone, but other infections and cancer do. Scientists are trying to develop a cure for the AIDS virus. There are three parts to finding the cure. The three parts are: 1. To devise a drug that will kill the HIV once it enters the body. 2. To create a vaccine that would prevent the disease. 3. To educate people world wide about the dangers of AIDS and how to prevent the HIV infection. In 1986, the first step was taken in AIDS prevention. AZT is a pill that has prolonged the lives of HIV infected patients. Ninety percent of patients who have taken the AZT pill are still alive after one year of being diagnosed. This is an increase of 50% without the pill. There are some side effects of AZT.

Of Mice and Mengood essays

Of Mice and Mengood essays The novel Of Mice and Men, by John Steinbeck, is about two men who are brought together and share few good times, such as each others company, and the more overwhelmingly the bad times. Both men fight the loneliness that was ramped during the Depression. The story begins in the foothills of Salinas, California, in the middle of the Great Depression. Here we meet two men, who are able to carry all of their possessions in a bindle, and are continually planning on how to get their own land and live off of the fat a da land. George, the mentally stronger of the two, tells his companion Lennie, how life is going to be on this piece of land. Lennie is constantly asking George to repeat his because it makes him feel good and this is understandable because Lennie has the mental capacity of a two year old. Before the two men are able to purchase this coveted piece of land that they are after, they need to save enough money. That is the reason they go to work on a barley ranch. This ranch wil l change their lives forever. While at the ranch, Lennie breaks the hand of the bosses son and then accidentally kills the wife of the son. After Lennie kills the woman, and other previous mishaps at previous jobs, George realizes that because of Lennies mental capability, or lack of it, Lennie will continue to hurt and maybe even kill other people. George decides to shoot Lennie in fear that if anyone else will get to him, that they will hurt him. Throughout this entire novel, there are many examples of loneliness. Steinbeck stresses the theme of loneliness through the characters of Crooks, Candy, and Curley's wife. The first character Steinbeck uses to express loneliness in his book is Crooks. Crooks is a crippled, black, ranch hand. He became crippled when a horse kicked him in the back. Also, because of his skin color, he is never allowed in the other mens bunk to play cards or just hang out. Crooks is all alone in th ...

The Mechanism of Dis2 Phosphorylation by Chk1 and Cell Cycle Dissertation

The Mechanism of Dis2 Phosphorylation by Chk1 and Cell Cycle Regulation - Dissertation Example PP1 and its role as a mitotic checkpoint xxxii 1.6. PP1 and cell cycle control xxxiv 1.7. Importance of regulatory subunits and their role in diseases xxxv 1.8. Human paralogues of Dis2 xli 1.9. Conclusion xliv Chapter 2 xlvii Materials and Methods xlvii 2.1. Preparation of media xlvii 2.2. Preparation of buffers xlviii 2.3. Preparation of stain l 2.4. Preparation of normal SDS-PAGE buffer and gels l 2.5. Preparation of PEMS solutions liii 2.6. Preparation of protein extracts for use in SDS-PAGE liv 2.7. Running of SDS-PAGE: lvii 2.8. Construction of yeast strains lviii 2.9. Preparation of membrane lx 2.10. Chk1-HA shift experiment lx 2.11. TCA protein extraction lxii 2.12. Immune localization of proteins in yeast cells lxiv 2.13. Drop test lxviii 2.14. Preparation of cells for imaging lxix 2.15. Acute cell survival lxxi Chapter 3 lxxiv Results lxxiv 3.1. Dephosphorylation of Chk1 at 40Â °C is not affected by Dis2 phosphatase lxxiv 3.2. Dephosphorylation of Hus1 at 40Â ° lxxviii 3. 3. Hypersensitivity to DNA damaging agent lxxxi 3.4. Structural changes to cells lxxxiv 3.5. Study on cell survival lxxxvi 3.6. Identification of hus1 isoforms xcii 3.7. Comparison of Dis2 with other proteins xciv Chapter 4 xcix Discussion xcix 4.1. Conclusion civ 5. Appendix cvi 5.1. Appendix – 1 Multiple sequence alignment of dis2 protein cvi 5.2. Appendix – 2 Alignment of dis2 from S. pombe with human protein serine/threonine phosphatase cviii 5.3. Appendix - 3 Significance sequence alignment of protein serine/threonine phosphatase-1 cxi Acknowledgment This thesis was made possible by the unrelenting support of my supervisors and peers. I thank the university and the department for providing me with the technical as well as educational support apart from laboratory facilities for carrying out this research. It has been a great pleasure to complete this thesis under the support and guidance of my professors. Hypothesis Chk1 kinase is phosphorylated at serine 345 in r esponse to DNA damage. Dis2 dephosphorylated this residue slowly when cells recover from a DNA damage-induced cell cycle arrest. A rise in temperature from 30Â °C to 40Â °C results in the rapid dephosphorylation of S345 by a yet unknown phosphatase. The purpose of this experiment is to investigate the requirement of Dis2 for the heat-induced phosphorylation and to investigate the cell cycle roles of this enzyme. Other phosphor-proteins such as Hus1 and Rad9 are also investigated. 1. Abstract Protein phosphatases are a group of enzymes which have very specific role in biological cell activities. Dis2 is a PP1 enzyme (serine-threonine phosphatase-1) which plays a key role in regulation of DNA damage signaling. Fission yeast Dis2 regulates the DNA damage respons by dephosphorylation of chk1 kinase at Ser 345. In eukaryotic cells, phosphorylation mainly occurs on three hydroxyl-containing amino acids, namely – serine, threonine, and tyrosine, of which serine is the predominant target. Dis2 dephosphorylates the DNA damage checkpoint kinase Chk1 (at Ser-345) to switch off the checkpoint signal. Interestingly, heat stress results in very rapid removal of the phosphate from Ser 345 by a yet unknown phosphatase. Given the requirement of Dis2 for the dephosphorylation of Ser 345 at the normal growth temperature of 30Â °C, this study was conducted to investigate the role of this phosphatase under heat stress condition modification of Ser 345 is easily detected as a band shift of the protein which changes from a closed, low activity conformation

SELF INCRIMINATION Research Paper Example | Topics and Well Written Essays - 2000 words

SELF INCRIMINATION - Research Paper Example Two main principles of the Fifth Amendment therefore include protection of rights of persons undergoing criminal proceedings in the courts, to further support the premise of innocent until proven guilty. Secondly, the principle of prevention of prosecution conduct likely to compel defendants to give their own incriminating evidence takes shape in the Fifth Amendment. Judges cannot compel individuals before court to give information that would directly affect negatively in their pursuit of exoneration in court proceedings. Other persons with an interest in the case cannot compel the defendant to give evidence against themselves within the precincts of the court (GetLegal, 2012). The Fifth Amendment therefore controls any influence that could alter the defendant’s opportunity to present their case before court with confidence that they will not face undue pressure to incriminate themselves, thereby destroying their enjoyment of right to be innocent until proven guilty. Another emergent theme in the Fifth Amendment is the active separation of powers in criminal proceedings, where the executive faces barring environment against use of force on witnesses’ rights. The interpretation of the Fifth Amendment has however faced various contestations with regard to the parties and conditions against which the Amendment gains enforcement authen tication. In Miranda v. Arizona, a case that took place in 1966 the United States Supreme Court defined the admissibility of evidence obtained irregularly from the defendant, particularly within the conditions of absence of an attorney to guide the defendant during questioning. According to the court’s argument, obtaining exculpatory and inculpatory statement in gathering prosecutorial evidence exposes the individual to conditions that may violate their own constitutional rights of informed consent. The right against

Improving Attendance in Statutory Education Essay Example for Free

Improving Attendance in Statutory Education Essay Under the Education Act 1996, the Council has a statutory duty to ensure children and young people receive fulltime, efficient education, which is suitable to the age, and ability and any special needs they may have. This is usually through attendance at school. The Education Welfare Service (EWS) is one agency which takes the lead role for the Council in supporting school attendance. It will do this through working with children and families, supporting schools and linking with other agencies including the legal system. The EWS will look at a whole range of ideas for why the children aren’t attending school and will look at solutions for this whether it be legal action or just working closely with all involved for example parents, teachers and the school. On the whole this is an extremely important agency which aims to get children into education and helps work out why they are not in education, however there are negative aspects to the agency as they may have to work closely with social services if the parents aren’t fulfilling there role and legal action may be taken again the parents aren’t fulfilling the responsibility although this is a negative aspect of the agency it is all in place for the overall well being of the child. Police can work with local schools and EWC, by undertaking local patrols to detect truancy and going to local areas where children may hide out. By having the police involved children and parents will be able to understand the severity of truancy and poor school attendance which is a positive outcome. This can then lead on to the Youth Offending Team (YOT) whose staff identifies school attendance issues and work actively to resolve them. The Council will work with agencies such as housing companies, Police, Connexions, YOT and voluntary organisations to develop protocols to identify children without school places. Overall these agencies are all there to help improve attendance in schools and all have the same aims, by working together with the school, agencies and organisiations the schools will be able to have the correct support in place for the children in and out of schools, parents and the teachers. The agencies are able to work out reasons for poor attendance and make sure issues are resolved. These organizations are here for a positive reason and to help children get the best education possible and cutting down on reasons for poor attendance. Explain the role of key individuals in improving whole school attendance. Educational Welfare officers- Once a child is registered at a school, it is the parents legal duty to make sure that the child attends school regularly. The role of Education Welfare Officers is to work closely with schools, children and their parents, and with agencies to make sure this happens. The educational welfare officers will work closely with these people to find out why children arent attending regularly and figure out soloutions to ensure this changes. If the parents fail to cooperate and the child does not return to regular attendance at school, the Education Welfare Service may issue a Fixed Penalty Notice or take legal action. Educational welfare officers can refer cases to other agencies such as social services, educational psychologists and health professionals. Ultimately their main responsibilities is to provide support to the children, the families and the school in all areas whether it to be advice on legal responsibilities, or building relationships between the school and the parents and making sure school attendance is at a maximum, if school attendance is not consistant then the educational welfare officers will look into reasons and solutions for this. Teaching Support Workers- Support teachers are in classrooms to support teachers in what they are trying to achieve, they are also there to help individuals who are in need of support when learning, Support teachers are able to give the individuals in need of help more time and focus to help them through areas of difficulties. Having Teaching supports workers available will therefore mean children will feel supported in weak areas and therefore more progress will be made by children which will also boost confidence. Children who are falling behind or children who do not understand specific areas of what they are being taught can become embarassed and withdrawn whilst lacking confidence this could lead to poor behaviour meaning suspension,exclusion,detention or missing school to avoid feeling embarrassed around peers. Having teaching support workers available will mean weak areas can be taregeted and help provided much quicker than just having one teacher in a classroom. Teaching support workers will be able to have the relevant training and guidance to help identify children who are struggling. These are people who are their to support children with any behaviour or learning needs. Headteachers- Most of the duties of a headteacher is managerial and to make sure the school is running properly whilst also making sure everything necessary is provided for staff and pupils. Head teachers will need to make sure specific training is given to identify children who are struggling, making sure there are policies and procedures in place and followed by staff to prevent bullying and equal opportunities. By making sure the children have the mose valuable expreience possible at school and working with children, parents and other agenicies to make sure everything is in place to keep attendace high, if children are struggling the support teacher are in place, if bullying is happening then this needs to be resolved quickly before the child becomes withdrawnand lacks confidence leading to poor attendance. The head teacher will be able to use educational welfare officers and other agencies to help find ways of improving the school and making sure all areas of a childrens welfare are covered and the child is offered the support needed to enjoy school and attend school attaining the best qualifications possible. Special Educational Coordinators- The Special Educational Needs Co-ordinator (SENCO), in collaboration with the head teacher and governing body, plays a key role in determining the strategic development of the Special Educational Needs (SEN) policy and provision in the school to raise the achievement of children with special educational needs. The SENCO takes day-to-day responsibility for the operation of the policy and co-ordination of the provision made for individual children with special educational needs, working closely with staff, parents and carers and other agencies. By having the special education needs co-ordinator this will mean that full support will be given to children in school meaning the chilldren can work to the maximum and achieve the most out of school with the full support and help from the teachers. This will also mean that children wont be embarrassed because they cannot keep up or understand the work and should hopefully stop the children turning to negative behaviour like missing school. This will enable the school to give the children the best experience possible with the best possible outcomes and increased attendance therefore increasing grades attained by children. Explain strategies that can be used to improve the attendance of individual children and young people and whole school attendance Have an attendance policy in place make sure the children are fully aware of the steps that will be taken in cases of non attendance. Whilst making sure that parents follow the procedure for days that children are of sick. Keep parents involved and build relationships with the parents using head teachers and teachers so that they are aware of any problems that maybe underlying at school at the present time which my result in non-attendance. It is also vital to make parents aware of any positive achievements that their son or daughter has achieved. Support available, makes sure that any children struggling in specific educational areas are identified as quickly as possible so that all relevant support and help can be put in place to help the child in the specified area. The school can work in partnership with the educational welfare officer and the local authority to help target specific areas of need. Use rewards and incentives to encourage attendance and punctuality such as certificates for high attendance and increased incentive for the higher attendance and punctuality as the year progresses. Once a child has been absent from school make sure they reintegrate into the school positively. Making sure teachers check they are ok, provide any missed work and provide a support group making sure this is available to the children if they need to talk-for example counselors. Use attendance checks to keep on top of and monitor all attendance for children this will help to discover any patterns in non attendance and help the school find a solution to this quicker therefore benefiting the children. Raising the profile of attendance so if a child fails to attend sending a letter out to parents straight away to make sure they are aware of this or asking for a reason why there was no attendance if the attendance falls below a certain level. Schools can use newsletters and parents evenings to bring this to parents and children’s attention.

Peyronies Disease :: essays research papers

Peyronie's disease What is Peyronie's disease? Peyronie's disease is a disorder affecting the penis that can cause:  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  a lump within the shaft of the penis  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  pain in the shaft of the penis  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  abnormal angulation of the erect penis ('bent' penis). Not all of these features are necessarily present, but, typically, a man would first notice a tender lump in the penis, which might later be followed by bending of the penis when erect, sometimes at very odd angles. The flaccid penis is not usually deformed. It is important to remember that a degree of upward (towards the head) angulation of the erect penis is quite normal and not a feature of Peyronie's disease. Good advice Noticing a lump in the penis can be a frightening experience. Men are often concerned that they have developed a cancer. Cancer within the penile shaft is very rare indeed, while Peyronie's disease is by far the most common cause of such lumps. If you find a lump, it is important to seek prompt medical advice, but you should not be too fearful that a serious cause will be found What causes Peyronie's disease? The penis consists of basically three cylinders, covered by several sheaths of tissue and, finally, by skin. A pair of corpora cavernosa form the erectile tissue that becomes engorged with blood during erection, acting like the inner tube of a tyre. They are surrounded by the tunica albuginea, a tough, inelastic, fibrous sheath, which might be compared with the tyre itself. When the penis becomes erect, the inner tubes (corpora cavernosa) inflate, filling the space within the tyre (tunica albugenia), making it more rigid. In Peyronie's disease, tough, fibrous plaques spontaneously appear within the tunica albugenia, and are felt as tender lumps. When the penis becomes erect, it inflates unevenly and tends to bend around the plaque, causing the characteristic deformed appearance of Peyronie's disease. Experts are not certain why some men get Peyronie's disease and others do not. Several factors might be involved, including:  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  genetics: occasionally the disease has a tendency to run in certain families (inherited or genetic predisposition), but this is not common.  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  injury: Peyronie's disease is more common after injury to the penis, such as penile fracture or forceful bending of the erect penis. It also occurs more frequently in men that give injections into the penis for the treatment of erectile dysfunction (impotence).  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  circulatory disorders: more men with Peyronie's disease seem to be affected by high blood pressure and hardening of the arteries (atherosclerosis), so these conditions might possibly be involved in its development.

Collaborative Practice in Health Care Essay

Collaborative practice in health care occurs when a member of the health care team consults with another member to provide patient care. Collaboration most often occurs between doctors and nurses. â€Å"Collaboration is defined as a relationship of interdependence; the ability to work together involves trust and respect not only of each other but of the work and perspectives each contributes to the care of the patient† (Phipps and Schaag, 1995, p. 19). Effective collaborative practice amongst all health care team members leads to continuity of care, professional interdependence, quality care and patient satisfaction and decreased costs. Ongoing collaboration between health care members results in mutual respect, trust and an appreciation of what each individual brings to the overall goal in rendering care to the client. The following vignette will provide the foundation for the discussion of collaborative care, differentiating between nursing diagnosis and collaborative proble ms, and potential barriers to successful collaboration. JG is a 74 year old married Hispanic male diagnosed with colon cancer. He had a history of prosthesis placement of his left lower leg; he is ambulatory. He is a diabetic on oral medications. He worked as a farm laborer. He lives with his wife she does not speak English she is a homemaker. He has a son who lives nearby and a nephew who periodically visits him. JG can understand some English. He does have some difficulty expressing his health concerns to the staff because of his limited vocabulary. His son or nephew brings JG to his clinic appointments. He receives weekly chemotherapy at the outpatient oncology clinic. The day I cared for JG he arrived at the clinic accompanied by his nephew. This was week seven of his treatment. His clothing was dirty, he smelled of stool, his fingernails were dirty, hair uncombed, he appeared to be dehydrated. He reported bowel movements of eight stools per day with complaints of occasional abdominal cramping. He denied nausea or loss of appetite. He stated that he was very tired and was not able to do much at home. His main concern was the frequency of his bowel movements. He reports having to go to the bathroom two to three times during the night and has episodes of soiling the bed. He reports that sometimes he does not feel the  urge to go. JG was wearing adult diapers. He expressed concern that it was getting expensive for him to purchase. The nephew confirmed that JG toileting has created a problem in the home. His nephew verbalized that JG had medication for diarrhea but ran out of it and he did not have the money to purchase the medication. When questioned why he was using a wheelchair he stated that his foot hurt to walk the distance from the lobby to the treatment room. He mentioned that it was probably due to an ingrown toe nail. He also asked how he could obtain a wheel chair for his personal use at home. Physical assessment revealed that he had a necrotic area on the ball of his left foot with surrounding redness, lost 12 pounds in six weeks, poor skin turgor, hyperactive bowel sou nds, and his blood pressure was slightly lower than baseline. In the ambulatory chemotherapy setting, the clients do not always see their physician every time they receive treatment. The nurse must ascertain when to collaborate with the physician on issues regarding the patients status, response to treatment, or toxicities that may be life threatening. It is essential that the nurse is capable to communicate effectively her-(Be careful with gender bias, nurses come in both genders.) observations to the physician. Collaborative problems are detected from the nurse’s assessment of the patient. The nurse’s monitoring of the patient status is to evaluate physiological complications that may threaten the patient’s integrity. Management of collaborative problems will include implementing physician prescribed and nurse prescribed actions to curtail escalation of the problem and preventing patient harm. From the nurse’s assessment, she also formulates a nursing diagnosis. The nursing diagnoses are stated in the form of the problem, the etiology and the symptoms that the nurse observes. Nursing diagnosis can include a current or potential problem, an at risk problem, or a wellness diagnosis. Nursing diagnosis provides the framework from which the nurse begins to devise a plan of care and nursing interventions. In the case of JG, there were two collaborative problems identified. Two  problems I collaborated with physician, these were: 1. JG is experiencing toxicity from the chemotherapy. There is potential for electrolyte imbalance, circulatory collapse. 2. The necrotic area on his foot was a new development in his condition. There is potential complication for infection The collaborative problems discussed with JG physician and nurse quickly resolved. JG did not receive his chemotherapy. He was given an injection of sandostatin LR to help minimize his diarrhea; a stat basic metabolic panel was obtained; and he was given intravenous hydration with potassium. The doctor made a referral to JG podiatrist for the next day to assess the integrity of his left foot. Listed are four, but not all, possible nursing diagnosis obtained from my assessment. 1. Diarrhea related to chemotherapy manifested by hyperactive bowel sounds and eight loose stools. 2. Bowel incontinence related to loss of rectal sphincter control and chemotherapy manifested by fecal odor, fecal staining of clothing, urgency. 3. Altered Nutrition related to colon cancer manifested by diarrhea, abdominal cramping. 4.Ineffective management of therapeutic regimen related to JG lack of knowledge of his disease manifested by his inability and unwillingness to manage his symptoms. Considering JG comments regarding his finances, his overall physical appearance and the comments from his nephew, I decided to consult with the social worker. I felt that a home visit or a thorough investigation of JG home situation was warranted. The social worker was able to arrange for in home support, and helping the patient with insurance issues so he could obtain the needed supplies. I did not think to enlist the participation of the dietician. In retrospect, the dietician would have been a valuable resource to assess JG caloric intake and recommendations for optimal nutrition. I felt that the above incident demonstrated collaboration amongst health care providers. The physician in this case was receptive to the nurse’s observations with respect to her capabilities of accurate assessment of the patient’s condition and potential complications. This is not always the case, barriers to collaboration are also inherent in the health care industry. Barriers occur in patient situations where the physician is not sympathetic or does not trust the nurse’s evaluation of patient condition. The nurse may have feelings of inferiority, lack of confidence and does not appropriately collaborate with the physician correct information. Conflicts in the goals desired for the patient is often cited as a barrier to collaboration. I recall an incident of a male patient diagnosed with metastatic breast cancer. His appearance was that of an individual who had been in a Nazi concentration camp. The nurse wondered why the physician was treating this man aggressively. In her mind, this patient was not an appropriate candidate to receive the particular treatment that was ordered. She feared the patient would not tolerate such an aggressive schedule and that it was pointless to put this poor man through treatment. The patient was diagnosed two years ago. He is still receiving treatments, he has gained weight and in October of last year he hiked to the summit of Mt. Whitney. Role conflict is another major barrier to collaboration. To deliver cost effective care, many institutions utilize nurse practitioners and physician assistants. Role conflict arises when practitioners have opposing views or expectations (Blais, Hayes, Kozier, & Erb, 2002). Role conflict and can lead to litigation. According to Resnick, physicians hesitate to collaborate informally with Nurse Practitioners for fear of being held liable for the actions of the Nurse Practitioner (Resnick, 2004). Clear definition of roles  for practitioners is essential to prevent misunderstanding. In conclusion, collaborative practice is the gold standard that health care practioners should strive towards. The nurse is central in determining the patient issues that warrant collaboration and she must be able to effectively communicate her observations. Collaborative practice minimizes complications that could lead to tragic outcomes. The ultimate goal of collaborative practice is to provide the quality service that each patient under our care deserves. References Blais, K.K., Hayes, J. S., Kozier, B. & Erb, G. (2002). Professional nursing practice: Concepts and perspectives (4th ed.). New Jersey: Prentice Hall. Phillps, W.J., & Schaag, H.A. (1995). Persepctives for health and illness. In Phipps, W.J, Cassmeyer, V.L., Sands, J. E., Lehman, M.K(Eds.), Medical surgical nursing concepts and clinical practice, p. 19. St. Luis, MO: Mosby. Resnick, B. (2004). Limiting litigation risk through collaborative practice. Geriatric Times, 5(4), 33. Retrieved March 21, 2004 from EBSCOhost database.

Kinds of Retributive Justice - Free Essay Example

Sample details Pages: 3 Words: 775 Downloads: 2 Date added: 2017/09/11 Category Advertising Essay Did you like this example? There are two distinct kinds of retributive justice. The classical definition embraces the idea that the amount of punishment must be proportional to the amount of harm caused by the offense. A more recent version, supported by Michael Davis, discharges this idea and replaces it with the idea that the amount of punishment must be proportional to the amount of unfair advantage gained by the wrongdoer. Don’t waste time! Our writers will create an original "Kinds of Retributive Justice" essay for you Create order Davis introduced this version of retributive justice in the early 1980s, at a time when retributive justice was making a recovery within the philosophy of law community, maybe due to the multiple failures of reform theory in the previous years. In the early period of all systems of law the redress of wrongs takes precedence over the enforcement of contract rights, and a rough sense of justice demands the infliction of proportionate loss and pain on the aggressor as he has inflicted on his victim. Incapacitation in the context of sentencing philosophy refers to the effect of a sentence in terms of positively preventing (rather than merely deterring) future offending. Imprisonment incapacitates the prisoner by removing them from the society against which they are deemed to have offended. Cutting off a hand of a thief is also an example; this acts to prevents further thefts in a drastic manner, in addition to its having a deterrent effect on others. Like deterrence, incapacitation can be specific to an individual and/or specific to a particular crime, or can be general in either respect. Deterrence is one of the primary objects of the Criminal Law. Its primary goal is to discourage members of society from committing criminal acts out of fear of punishment. The most powerful deterrent would be a criminal justice system that guaranteed with certainty that all persons who broke the law would be apprehended, convicted, and punished, and would receive no personal benefit from their misconduct. United States policy of deterrence during the Cold War underwent significant variations. The early stages of the Cold War were generally characterized by ideology of Containment, an aggressive stance on behalf of the United States especially regarding developing nations under their sphere of influence. Rehabilitation means to restore to useful life, as through therapy and education or To restore to good condition, operation, or capacity. The assumption of rehabilitation is that people are not natively criminal and that it is possible to restore a criminal to a useful life, to a life in which they contribute to themselves and to society. Rather than punishing the harm out of a criminal, rehabilitation would seek, by means of education or therapy, to bring a criminal into a more normal state of mind, or into an attitude which would be helpful to society, rather than be harmful to society. Although the importance of inflicting punishment on those persons who breach the law, so as to maintain social order, is retained, the importance of rehabilitation is also given priority. Humanitarians have, over the years, supported rehabilitation as an alternative, even for capital punishment. Restoration is to return what has been unjustly taken; to place the owner of a thing in the state in which he formerly was. By restitution is understood not only the return of the thing itself, but all its accessories. It is to return the thing and its fruits. Retributive justice began to replace this system following the Norman invasion of Britain. William the Conquerors son, Henry I, issued laws detailing offenses against the â€Å"king’s peace. † In the 20th century, restorative justice started becoming more popular. In my personal opinion I just think we need to let them all ROT in prison depending on the crime of course. If I had to choose from all of the choices I think that rehab is one of the better choices because it is trying to make the person a constructive part of society and gives them another chance but I think that their should be a limit to how many times someone can try to be rehabilitated, like two. I think two is a good number because the first time is on them and pretty much everyone deserves a second chance, and then if they mess up a again after their first chance try again cause everyone makes mistakes and everyone has those days, if they mess up again they apparently won’t learn their lesson. [pic]A Law Dictionary, Adapted to the Constitution and Laws of the United States. By John Bouvier. Published 1856. Martin, Jacqueline (2005). The English Legal System (4th ed. ), p. 176. London: Hodder Arnold. ISBN 0-340-89991-3. Cavadino, M Dignan, J. (1997). The Penal System: An Introduction (2nd ed. ), p. 39. London: Sage.